Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Neut_0976Sodium/proton antiporter, CPA1 family; PFAM: sodium/hydrogen exchanger; KEGG: pae:PA3739 probable sodium/hydrogen antiporter; TC 2.A.36. (603 aa)    
Predicted Functional Partners:
Neut_0318
Kef-type potassium/proton antiporter, CPA2 family; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: noc:Noc_2952 sodium/hydrogen exchanger, TrkA-N; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
 
 0.687
apaH
Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
   0.664
Neut_0500
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.455
Neut_1131
Cation transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
 
 
 
 0.444
Neut_1697
Multicomponent K+:H+ antiporter subunit A; KEGG: neu:NE1901 NADH-ubiquinone oxidoreductase subunit 5 (chain L); TIGRFAM: monovalent cation/H+ antiporter, subunit 1; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I); Na+/H+ antiporter MnhB subunit-related protein; TC 2.A.63.1.1; TC 2.A.63.1.1.
      
 0.432
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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