Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Neut_0979PFAM: pyruvate kinase; KEGG: nmu:Nmul_A1507 pyruvate kinase; Belongs to the pyruvate kinase family. (483 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.982
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: neu:NE2263 phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 0.941
pgi-2
PFAM: ROK family protein; phosphoglucose isomerase (PGI); KEGG: dra:DR1742 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.941
Neut_1304
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: neu:NE0899 D-isomer specific 2-hydroxyacid dehydrogenase.
 
 0.934
Neut_0596
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: neu:NE0438 putative malate oxidoreductase (malic enzyme).
  
 0.931
Neut_1608
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.920
Neut_1580
PFAM: pyruvate kinase; KEGG: neu:NE0325 pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 
0.916
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.913
Neut_0868
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.912
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.912
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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