node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Neut_0135 | Neut_1570 | Neut_0135 | Neut_1570 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | 0.921 |
Neut_0135 | trpA | Neut_0135 | Neut_1153 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.980 |
Neut_0135 | trpB | Neut_0135 | Neut_1152 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.978 |
Neut_0135 | trpC | Neut_0135 | Neut_0133 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: neu:NE0012 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |
Neut_0135 | trpD | Neut_0135 | Neut_0134 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
Neut_0135 | trpE | Neut_0135 | Neut_2098 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.999 |
Neut_0135 | trpF | Neut_0135 | Neut_1151 | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: neu:NE0692 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. | 0.998 |
Neut_1155 | accD | Neut_1155 | Neut_1154 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: neu:NE0696 cytoplasmic peptidoglycan synthetases, C-terminal; Belongs to the folylpolyglutamate synthase family. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.777 |
Neut_1155 | trpA | Neut_1155 | Neut_1153 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: neu:NE0696 cytoplasmic peptidoglycan synthetases, C-terminal; Belongs to the folylpolyglutamate synthase family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.729 |
Neut_1155 | trpB | Neut_1155 | Neut_1152 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: neu:NE0696 cytoplasmic peptidoglycan synthetases, C-terminal; Belongs to the folylpolyglutamate synthase family. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.558 |
Neut_1155 | trpF | Neut_1155 | Neut_1151 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: neu:NE0696 cytoplasmic peptidoglycan synthetases, C-terminal; Belongs to the folylpolyglutamate synthase family. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: neu:NE0692 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. | 0.640 |
Neut_1155 | truA | Neut_1155 | Neut_1150 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: neu:NE0696 cytoplasmic peptidoglycan synthetases, C-terminal; Belongs to the folylpolyglutamate synthase family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.691 |
Neut_1570 | Neut_0135 | Neut_1570 | Neut_0135 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: neu:NE0014 panthranilate synthase component II (glutamine amido-transferase) protein. | 0.921 |
Neut_1570 | trpA | Neut_1570 | Neut_1153 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.688 |
Neut_1570 | trpB | Neut_1570 | Neut_1152 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.617 |
Neut_1570 | trpC | Neut_1570 | Neut_0133 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: neu:NE0012 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.692 |
Neut_1570 | trpD | Neut_1570 | Neut_0134 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.709 |
Neut_1570 | trpE | Neut_1570 | Neut_2098 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.967 |
Neut_1570 | trpF | Neut_1570 | Neut_1151 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: neu:NE0692 N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Belongs to the TrpF family. | 0.717 |
accD | Neut_1155 | Neut_1154 | Neut_1155 | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: neu:NE0696 cytoplasmic peptidoglycan synthetases, C-terminal; Belongs to the folylpolyglutamate synthase family. | 0.777 |