| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Neut_0219 | Neut_1570 | Neut_0219 | Neut_1570 | KEGG: neu:NE0049 sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | 0.592 |
| Neut_0219 | nadE | Neut_0219 | Neut_2008 | KEGG: neu:NE0049 sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.691 |
| Neut_1191 | Neut_1192 | Neut_1191 | Neut_1192 | NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: neu:NE0859 alanine dehydrogenase and pyridine nucleotide transhydrogenase. | KEGG: neu:NE0860 probable transmembrane NAD(P) transhydrogenase (alpha subunit part 2). | 0.999 |
| Neut_1191 | Neut_1193 | Neut_1191 | Neut_1193 | NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: neu:NE0859 alanine dehydrogenase and pyridine nucleotide transhydrogenase. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
| Neut_1191 | nadD | Neut_1191 | Neut_1610 | NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: neu:NE0859 alanine dehydrogenase and pyridine nucleotide transhydrogenase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.900 |
| Neut_1191 | nadE | Neut_1191 | Neut_2008 | NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: neu:NE0859 alanine dehydrogenase and pyridine nucleotide transhydrogenase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.907 |
| Neut_1191 | nadK | Neut_1191 | Neut_0768 | NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: neu:NE0859 alanine dehydrogenase and pyridine nucleotide transhydrogenase. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.914 |
| Neut_1192 | Neut_1191 | Neut_1192 | Neut_1191 | KEGG: neu:NE0860 probable transmembrane NAD(P) transhydrogenase (alpha subunit part 2). | NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: neu:NE0859 alanine dehydrogenase and pyridine nucleotide transhydrogenase. | 0.999 |
| Neut_1192 | Neut_1193 | Neut_1192 | Neut_1193 | KEGG: neu:NE0860 probable transmembrane NAD(P) transhydrogenase (alpha subunit part 2). | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
| Neut_1192 | nadD | Neut_1192 | Neut_1610 | KEGG: neu:NE0860 probable transmembrane NAD(P) transhydrogenase (alpha subunit part 2). | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.900 |
| Neut_1192 | nadE | Neut_1192 | Neut_2008 | KEGG: neu:NE0860 probable transmembrane NAD(P) transhydrogenase (alpha subunit part 2). | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.907 |
| Neut_1192 | nadK | Neut_1192 | Neut_0768 | KEGG: neu:NE0860 probable transmembrane NAD(P) transhydrogenase (alpha subunit part 2). | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.913 |
| Neut_1193 | Neut_1191 | Neut_1193 | Neut_1191 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: neu:NE0859 alanine dehydrogenase and pyridine nucleotide transhydrogenase. | 0.999 |
| Neut_1193 | Neut_1192 | Neut_1193 | Neut_1192 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | KEGG: neu:NE0860 probable transmembrane NAD(P) transhydrogenase (alpha subunit part 2). | 0.999 |
| Neut_1193 | nadD | Neut_1193 | Neut_1610 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.900 |
| Neut_1193 | nadE | Neut_1193 | Neut_2008 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.937 |
| Neut_1193 | nadK | Neut_1193 | Neut_0768 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.907 |
| Neut_1570 | Neut_0219 | Neut_1570 | Neut_0219 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | KEGG: neu:NE0049 sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | 0.592 |
| Neut_1570 | nadE | Neut_1570 | Neut_2008 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: neu:NE0335 prephenate dehydratase (PDT):chorismate mutase:ACT domain. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.728 |
| Neut_2004 | nadE | Neut_2004 | Neut_2008 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.710 |