| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Neut_0116 | Neut_0117 | Neut_0116 | Neut_0117 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: eba:ebB77 single-strand DNA-binding protein. | 0.928 |
| Neut_0116 | Neut_0219 | Neut_0116 | Neut_0219 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | KEGG: neu:NE0049 sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | 0.576 |
| Neut_0116 | Neut_2461 | Neut_0116 | Neut_2461 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.586 |
| Neut_0116 | dnaQ | Neut_0116 | Neut_2175 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.412 |
| Neut_0116 | polA | Neut_0116 | Neut_0778 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.759 |
| Neut_0116 | rnhA | Neut_0116 | Neut_2176 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.698 |
| Neut_0116 | rnhB | Neut_0116 | Neut_2024 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.416 |
| Neut_0117 | Neut_0116 | Neut_0117 | Neut_0116 | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: eba:ebB77 single-strand DNA-binding protein. | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | 0.928 |
| Neut_0117 | Neut_2461 | Neut_0117 | Neut_2461 | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: eba:ebB77 single-strand DNA-binding protein. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.900 |
| Neut_0117 | polA | Neut_0117 | Neut_0778 | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: eba:ebB77 single-strand DNA-binding protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.755 |
| Neut_0117 | rnhA | Neut_0117 | Neut_2176 | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: eba:ebB77 single-strand DNA-binding protein. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.763 |
| Neut_0219 | Neut_0116 | Neut_0219 | Neut_0116 | KEGG: neu:NE0049 sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | 0.576 |
| Neut_0219 | polA | Neut_0219 | Neut_0778 | KEGG: neu:NE0049 sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.655 |
| Neut_0219 | rnhA | Neut_0219 | Neut_2176 | KEGG: neu:NE0049 sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.533 |
| Neut_2177 | dnaQ | Neut_2177 | Neut_2175 | KEGG: neu:NE0139 generic methyl-transferase. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.726 |
| Neut_2177 | gloB | Neut_2177 | Neut_2178 | KEGG: neu:NE0139 generic methyl-transferase. | Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. | 0.690 |
| Neut_2177 | rnhA | Neut_2177 | Neut_2176 | KEGG: neu:NE0139 generic methyl-transferase. | RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.871 |
| Neut_2461 | Neut_0116 | Neut_2461 | Neut_0116 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | 0.586 |
| Neut_2461 | Neut_0117 | Neut_2461 | Neut_0117 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: eba:ebB77 single-strand DNA-binding protein. | 0.900 |
| Neut_2461 | polA | Neut_2461 | Neut_0778 | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.826 |