Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Neut_2276PFAM: protein of unknown function UPF0118; KEGG: neu:NE0089 domain of unknown function DUF20. (363 aa)    
Predicted Functional Partners:
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: neu:NE0088 phosphoribosylaminoimidazole synthetase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
       0.689
purC
KEGG: neu:NE0866 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.
      0.682
Neut_2279
KEGG: neu:NE0086 hypothetical protein.
       0.632
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.630
Neut_2280
PFAM: Fmu (Sun) domain protein; KEGG: neu:NE0085 SAM (and some other nucleotide) binding motif; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
       0.609
Neut_2275
KEGG: nmu:Nmul_A0578 hypothetical protein.
       0.581
Neut_0318
Kef-type potassium/proton antiporter, CPA2 family; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: noc:Noc_2952 sodium/hydrogen exchanger, TrkA-N; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
    0.414
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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