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STRINGSTRING
Neut_2425 protein (Nitrosomonas eutropha) - STRING interaction network
"Neut_2425" - PFAM: SMC domain protein in Nitrosomonas eutropha
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Neut_2425PFAM- SMC domain protein; KEGG- noc-Noc_0704 ATP-dependent dsDNA exonuclease (SbcC) (1083 aa)    
Predicted Functional Partners:
sbcD
Nuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3’->5’ double strand exonuclease that can open hairpins. It also has a 5’ single-strand endonuclease activity (414 aa)
 
  0.998
Neut_1267
Uncharacterized protein; KEGG- neu-NE1390 serine/threonine specific protein phosphatase-Exonuclease SbcD (104 aa)
 
 
  0.936
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (906 aa)
   
 
  0.598
Neut_2545
PFAM- UvrD/REP helicase; KEGG- fnu-FN0524 DNA helicase II; Belongs to the helicase family. UvrD subfamily (971 aa)
   
 
  0.580
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (343 aa)
   
 
  0.565
Neut_0161
KEGG- noc-Noc_0060 ATP-binding region, ATPase-like (290 aa)
   
 
      0.467
recD
RecBCD enzyme subunit RecD; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3’ direction. Cuts ssDNA a few nucleotides 3’ to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3’-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] (680 aa)
 
 
  0.450
Neut_2216
TIGRFAM- CRISPR-associated protein, Csm1 family; KEGG- neu-NE0123 hypothetical protein (872 aa)
       
      0.450
Neut_0131
Exonuclease RecJ; TIGRFAM- single-stranded-DNA-specific exonuclease RecJ; PFAM- phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG- neu-NE0010 single-stranded-DNA-specific exonuclease (589 aa)
         
  0.422
Neut_2523
TIGRFAM- ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM- helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG- neu-NE2564 ATP-dependent DNA helicase RecQ (539 aa)
   
 
  0.421
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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