| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Neut_0002 | Neut_0116 | Neut_0002 | Neut_0116 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | 0.561 |
| Neut_0002 | mnmG | Neut_0002 | Neut_2437 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.564 |
| Neut_0002 | mutL | Neut_0002 | Neut_1828 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.936 |
| Neut_0002 | rsmG | Neut_0002 | Neut_2436 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.491 |
| Neut_0002 | yidC | Neut_0002 | Neut_2154 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.563 |
| Neut_0116 | Neut_0002 | Neut_0116 | Neut_0002 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.561 |
| Neut_0116 | Neut_1034 | Neut_0116 | Neut_1034 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | PFAM: GTP-binding protein, HSR1-related; KEGG: neu:NE0587 hypothetical protein. | 0.416 |
| Neut_0116 | Neut_2434 | Neut_0116 | Neut_2434 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: neu:NE2473 ParB-like nuclease domain:ParB-like partition protein; Belongs to the ParB family. | 0.515 |
| Neut_0116 | Neut_2435 | Neut_0116 | Neut_2435 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: neu:NE2474 ParA family ATPase. | 0.434 |
| Neut_0116 | mnmE | Neut_0116 | Neut_2155 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.416 |
| Neut_0116 | mnmG | Neut_0116 | Neut_2437 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.579 |
| Neut_0116 | mutL | Neut_0116 | Neut_1828 | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.569 |
| Neut_1034 | Neut_0116 | Neut_1034 | Neut_0116 | PFAM: GTP-binding protein, HSR1-related; KEGG: neu:NE0587 hypothetical protein. | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | 0.416 |
| Neut_1034 | mnmG | Neut_1034 | Neut_2437 | PFAM: GTP-binding protein, HSR1-related; KEGG: neu:NE0587 hypothetical protein. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.964 |
| Neut_1034 | rsmG | Neut_1034 | Neut_2436 | PFAM: GTP-binding protein, HSR1-related; KEGG: neu:NE0587 hypothetical protein. | 16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.808 |
| Neut_2434 | Neut_0116 | Neut_2434 | Neut_0116 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: neu:NE2473 ParB-like nuclease domain:ParB-like partition protein; Belongs to the ParB family. | KEGG: rme:Rmet_2298 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein. | 0.515 |
| Neut_2434 | Neut_2435 | Neut_2434 | Neut_2435 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: neu:NE2473 ParB-like nuclease domain:ParB-like partition protein; Belongs to the ParB family. | Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: neu:NE2474 ParA family ATPase. | 0.980 |
| Neut_2434 | mnmE | Neut_2434 | Neut_2155 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: neu:NE2473 ParB-like nuclease domain:ParB-like partition protein; Belongs to the ParB family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.542 |
| Neut_2434 | mnmG | Neut_2434 | Neut_2437 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: neu:NE2473 ParB-like nuclease domain:ParB-like partition protein; Belongs to the ParB family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.676 |
| Neut_2434 | rsmG | Neut_2434 | Neut_2436 | Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: neu:NE2473 ParB-like nuclease domain:ParB-like partition protein; Belongs to the ParB family. | 16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.867 |