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fpg protein (Nitrosomonas eutropha) - STRING interaction network
"fpg" - Formamidopyrimidine-DNA glycosylase in Nitrosomonas eutropha
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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Experiments
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[Homology]
Score
fpgFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3’- and 5’-phosphates (271 aa)    
Predicted Functional Partners:
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family (203 aa)
 
   
  0.935
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (906 aa)
 
   
  0.858
Neut_2511
KEGG- neu-NE2551 hypothetical protein (450 aa)
              0.760
Neut_2309
TIGRFAM- A/G-specific adenine glycosylase; PFAM- helix-hairpin-helix motif; HhH-GPD family protein; KEGG- neu-NE0056 HhH-GPD (376 aa)
 
 
  0.750
msrA
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (419 aa)
   
   
  0.719
Neut_2510
KEGG- neu-NE2550 putative ABC-2 type transport system permease protein (248 aa)
              0.714
Neut_0728
TIGRFAM- DNA internalization-related competence protein ComEC/Rec2; PFAM- beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG- neu-NE2408 DNA internalization-related competence protein ComEC/Rec2 (799 aa)
         
  0.685
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1300 aa)
 
   
  0.670
Neut_2509
ABC transporter-related protein; PFAM- ABC transporter related; SMART- AAA ATPase; KEGG- neu-NE2549 ATPase component ABC-type multidrug transport system (252 aa)
              0.651
ybeY
Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3’ terminus of the 16S rRNA (141 aa)
   
 
  0.643
Your Current Organism:
Nitrosomonas eutropha
NCBI taxonomy Id: 335283
Other names: N. eutropha C91, Nitrosomonas eutropha, Nitrosomonas eutropha C91, Nitrosomonas eutropha str. C91, Nitrosomonas eutropha strain C91
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