STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABE74529.1Aconitase; Belongs to the aconitase/IPM isomerase family. (867 aa)    
Predicted Functional Partners:
ABE74098.1
Isocitrate dehydrogenase (NADP).
  
 
 0.976
ABE73890.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.962
ABE75083.1
2-methylcitrate dehydratase.
 
   
 0.933
ABE74099.1
Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family.
  
 
 0.932
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.924
ABE75087.1
2-methylaconitate cis-trans isomerase.
 
  
 0.919
ABE76161.1
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.914
ABE75637.1
Isocitrate lyase.
     
 0.909
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.847
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.809
Your Current Organism:
Psychrobacter cryohalolentis
NCBI taxonomy Id: 335284
Other names: P. cryohalolentis K5, Psychrobacter cryohalolentis K5, Psychrobacter cryohalolentis str. K5, Psychrobacter cryohalolentis strain K5
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