| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABE74232.1 | ABE74783.1 | Pcryo_0449 | Pcryo_1002 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.726 |
| ABE74232.1 | ABE75105.1 | Pcryo_0449 | Pcryo_1324 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | uroporphyrinogen-III C-methyltransferase. | 0.680 |
| ABE74232.1 | cobS | Pcryo_0449 | Pcryo_1027 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.495 |
| ABE74232.1 | cobT | Pcryo_0449 | Pcryo_1026 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.484 |
| ABE74232.1 | cysG | Pcryo_0449 | Pcryo_1397 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.680 |
| ABE74783.1 | ABE74232.1 | Pcryo_1002 | Pcryo_0449 | ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.726 |
| ABE74783.1 | ABE75105.1 | Pcryo_1002 | Pcryo_1324 | ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | uroporphyrinogen-III C-methyltransferase. | 0.411 |
| ABE74783.1 | cobS | Pcryo_1002 | Pcryo_1027 | ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.918 |
| ABE74783.1 | cysG | Pcryo_1002 | Pcryo_1397 | ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Precorrin-2 dehydrogenase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.487 |
| ABE74805.1 | ABE74806.1 | Pcryo_1024 | Pcryo_1025 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | Predicted D-glycerate permease; TC 2.A.8.1.6. | 0.905 |
| ABE74805.1 | ABE74809.1 | Pcryo_1024 | Pcryo_1028 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | Phosphoglycerate mutase. | 0.400 |
| ABE74805.1 | cobS | Pcryo_1024 | Pcryo_1027 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.501 |
| ABE74805.1 | cobT | Pcryo_1024 | Pcryo_1026 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.501 |
| ABE74806.1 | ABE74805.1 | Pcryo_1025 | Pcryo_1024 | Predicted D-glycerate permease; TC 2.A.8.1.6. | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.905 |
| ABE74806.1 | ABE74809.1 | Pcryo_1025 | Pcryo_1028 | Predicted D-glycerate permease; TC 2.A.8.1.6. | Phosphoglycerate mutase. | 0.413 |
| ABE74806.1 | cobS | Pcryo_1025 | Pcryo_1027 | Predicted D-glycerate permease; TC 2.A.8.1.6. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.493 |
| ABE74806.1 | cobT | Pcryo_1025 | Pcryo_1026 | Predicted D-glycerate permease; TC 2.A.8.1.6. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.493 |
| ABE74809.1 | ABE74805.1 | Pcryo_1028 | Pcryo_1024 | Phosphoglycerate mutase. | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.400 |
| ABE74809.1 | ABE74806.1 | Pcryo_1028 | Pcryo_1025 | Phosphoglycerate mutase. | Predicted D-glycerate permease; TC 2.A.8.1.6. | 0.413 |
| ABE74809.1 | cobS | Pcryo_1028 | Pcryo_1027 | Phosphoglycerate mutase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.994 |