STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0047Transcriptional regulator, AbrB family; KEGG: tte:TTE0106 transcription regulator AbrB. (83 aa)    
Predicted Functional Partners:
Swol_0590
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.778
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.635
GrkA
grkA; KEGG: grkA; spore germination protein, GrkA.
  
   
 0.629
Swol_2375
KEGG: sth:STH103 stage III sporulation protein D.
  
   
 0.626
Swol_1322
Conserved hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.624
Swol_0078
KEGG: tte:TTE2379 germination protein.
  
   
 0.622
Swol_0063
KEGG: tte:TTE2552 pro-sigma-E processing factor spoIIR.
  
   
 0.550
Swol_0627
KEGG: mta:Moth_1375 stage V sporulation AD.
  
   
 0.549
Swol_0628
KEGG: mta:Moth_1374 SpoVA protein.
  
     0.518
Swol_0589
SpoIVB peptidase. Serine peptidase. MEROPS family S55; KEGG: dsy:DSY2342 hypothetical protein.
  
     0.493
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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