Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swol_0080KEGG: mta:Moth_0083 transcriptional regulator, AbrB family. (186 aa)    
Predicted Functional Partners:
Swol_2375
KEGG: sth:STH103 stage III sporulation protein D.
  
  
 0.868
Swol_0063
KEGG: tte:TTE2552 pro-sigma-E processing factor spoIIR.
  
   
 0.842
Swol_0627
KEGG: mta:Moth_1375 stage V sporulation AD.
  
   
 0.831
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.830
Swol_0590
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.828
Swol_0093
KEGG: tte:TTE2396 serine phosphatase RsbU, regulator of sigma subunit.
 
   
 0.813
Swol_0835
Sporulation sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
    0.810
Swol_0550
KEGG: tte:TTE1283 stage III sporulation protein spoIIIAA.
  
   
 0.807
Swol_0085
KEGG: tte:TTE2450 hypothetical protein.
 
     0.805
Swol_0836
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.797
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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