Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swol_0093KEGG: tte:TTE2396 serine phosphatase RsbU, regulator of sigma subunit. (824 aa)    
Predicted Functional Partners:
Swol_0834
Sporulation factor SpoIIGA. Unknown type peptidase. MEROPS family U04; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.948
Swol_0063
KEGG: tte:TTE2552 pro-sigma-E processing factor spoIIR.
  
   
 0.856
Swol_2375
KEGG: sth:STH103 stage III sporulation protein D.
  
   
 0.839
Swol_0550
KEGG: tte:TTE1283 stage III sporulation protein spoIIIAA.
  
   
 0.825
Swol_1322
Conserved hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.818
Swol_0080
KEGG: mta:Moth_0083 transcriptional regulator, AbrB family.
 
   
 0.813
Swol_0836
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.812
Swol_1586
KEGG: mta:Moth_0578 hypothetical protein.
  
   
 0.797
Swol_0556
Hypothetical protein; KEGG: mta:Moth_1530 stage III sporulation protein AG.
  
   
 0.777
Swol_0590
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.776
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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