Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0318KEGG: mta:Moth_1277 small GTP-binding protein domain. (402 aa)    
Predicted Functional Partners:
Swol_1022
KEGG: tte:TTE1568 thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
  
 0.964
Swol_1020
KEGG: tte:TTE1073 Biotin synthase and related enzymes.
   
 0.956
Swol_1023
Uncharacterized protein; Ortholog of Thermotoga maritima GenBank Accession Number AAD36341; KEGG: cac:CAC0487 uncharacterized protein, ortholog of Thermotoga maritima (4981823).
 
    0.809
Swol_1925
KEGG: sat:SYN_01370 iron only hydrogenase large subunit.
 
   
 0.778
Swol_2436
KEGG: det:DET0147 [Fe] hydrogenase, large subunit HymC, putative.
 
   
 0.776
Swol_1017
KEGG: mta:Moth_1717 iron hydrogenase, small subunit.
 
   
 0.773
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
 
 0.771
rpmH
KEGG: son:SO0007 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
  
 
 0.759
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 
 0.757
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.756
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
Server load: low (12%) [HD]