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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0375KEGG: dsy:DSY3883 hypothetical protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (390 aa)    
Predicted Functional Partners:
Swol_0559
Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.955
Swol_0308
Acetyl-CoA C-acetyltransferase; KEGG: gme:Gmet_2213 thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.924
Swol_0675
Acetyl-CoA C-acetyltransferase; KEGG: gme:Gmet_2213 thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.924
Swol_0789
Acetyl-CoA C-acetyltransferase; KEGG: gme:Gmet_2213 thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.924
Swol_1486
Acetyl-CoA C-acetyltransferase; KEGG: dsy:DSY1567 hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.924
Swol_1934
acetyl-CoA acetyltransferase; Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Probably catalyzes the beta- keto thiolysis of acetoacetyl-CoA, leading to 2 acetyl-CoA molecules.
  
 
 0.924
Swol_2051
acetyl-CoA acetyltransferase / 3-ketoacyl-CoA thiolase; KEGG: ctc:CTC00312 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.924
Swol_2139
KEGG: mta:Moth_2251 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 
0.920
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
  
 
0.916
Swol_0036
KEGG: chy:CHY_0043 putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit.
   
 
 0.908
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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