close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0419KEGG: mmp:MMP0831 uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family. (348 aa)    
Predicted Functional Partners:
Swol_0418
Dimethylamine corrinoid protein; KEGG: mmp:MMP0829 coenzyme B12-binding:cobalamin-dependent methionine synthase, B12-binding.
 
 0.996
Swol_0420
KEGG: mmp:MMP0832 hypothetical protein.
 
    0.947
Swol_0421
KEGG: mmp:MMP0833 hypothetical protein.
 
  
 0.914
Swol_0417
KEGG: mmp:MMP0830 uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family.
 
   
0.837
Swol_0422
KEGG: mmp:MMP0834 uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family.
 
    
0.768
Swol_0649
KEGG: tte:TTE1028 hypothetical protein.
 
    0.741
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 
 0.704
Swol_0687
uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; KEGG: dsy:DSY2224 hypothetical protein.
  
  
 0.533
Swol_0601
KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator.
     
 0.505
Swol_1442
Methionine synthase (B12-dependent); KEGG: pca:Pcar_2722 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation.
  
  
 0.504
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.