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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0452KEGG: chy:CHY_0311 putative CoA-substrate-specific enzyme activase. (251 aa)    
Predicted Functional Partners:
Swol_0450
KEGG: pca:Pcar_2726 hypothetical protein.
 
 0.916
Swol_0410
KEGG: gsu:GSU2519 (R)-2-hydroxyglutaryl-CoA dehydratase beta-subunit, putative.
 
 0.888
Swol_0427
KEGG: tde:TDE0392 (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative.
 
 0.887
Swol_0412
KEGG: tde:TDE0389 (R)-2-hydroxyglutaryl-CoA dehydratase, beta subunit, putative.
 
 0.864
Swol_2559
KEGG: mta:Moth_1151 hypothetical protein.
 
     0.751
Swol_0631
KEGG: mta:Moth_1371 hypothetical protein.
 
   
 0.585
Swol_2558
KEGG: mta:Moth_1150 hypothetical protein.
 
   
 0.575
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
       0.571
Swol_0454
HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.571
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.450
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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