STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0519Pyruvate carboxylase, PYKA; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1144 aa)    
Predicted Functional Partners:
Swol_2040
KEGG: tte:TTE1815 pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.964
Swol_0558
KEGG: chy:CHY_1999 oxaloacetate decarboxylase, alpha subunit.
 
 
0.962
birA
Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 0.961
Swol_1512
KEGG: mta:Moth_0607 pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
  
 
 0.948
Swol_0036
KEGG: chy:CHY_0043 putative keto/oxoacid ferredoxin oxidoreductase, alpha subunit.
     
 0.908
Swol_0037
KEGG: chy:CHY_0044 putative keto/oxoacid ferredoxin oxidoreductase, beta subunit.
     
 0.908
Swol_1048
KEGG: bcz:BCZK0420 formate C-acetyltransferase (formate acetyltransferase) (pyruvate formate-lyase).
     
 0.908
Swol_1374
KEGG: ctc:CTC02525 pyruvate synthase subunit porB.
     
 0.908
Swol_1375
Pyruvate ferredoxin oxidoreductase, alpha subunit; KEGG: ctc:CTC02526 pyruvate synthase subunit porA.
     
 0.908
Swol_1399
KEGG: chy:CHY_0576 putative keto/oxoacid ferredoxin oxidoreductase, beta subunit.
     
 0.908
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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