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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0683KEGG: sat:SYN_02276 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. (225 aa)    
Predicted Functional Partners:
Swol_0687
uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; KEGG: dsy:DSY2224 hypothetical protein.
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.907
hemL
KEGG: chy:CHY_1212 glutamate-1-semialdehyde-2,1-aminomutase.
   
 0.674
Swol_0690
KEGG: mta:Moth_1246 porphobilinogen synthase; Belongs to the ALAD family.
 
   
 0.668
Swol_2054
KEGG: cpe:CPE1014 probable flavoprotein.
 
  
 0.617
tatA
Twin-arginine translocation protein, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
       0.597
Swol_1442
Methionine synthase (B12-dependent); KEGG: pca:Pcar_2722 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation.
     
 0.519
Swol_1405
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; KEGG: cac:CAC1372 cobalamin biosynthesis enzyme CobT.
 
  
 0.503
Swol_0698
Putative iron-sulfur-binding reductase; Oxidoreductase involved in syntrophic growth of S.wolfei with butyrate. Is presumed to link the electron flow from butyryl-CoA dehydrogenases to the membrane, in conjunction with the electron transfer flavoprotein EtfAB. May transfer electrons to the menaquinone pool of the membrane.
  
  
 0.497
birA
Transcriptional repressor of the biotin operon / biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.465
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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