STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0690KEGG: mta:Moth_1246 porphobilinogen synthase; Belongs to the ALAD family. (326 aa)    
Predicted Functional Partners:
Swol_0687
uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; KEGG: dsy:DSY2224 hypothetical protein.
 
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.997
hemL
KEGG: chy:CHY_1212 glutamate-1-semialdehyde-2,1-aminomutase.
 
 
 0.994
Swol_0203
Aminotransferase; KEGG: pmt:PMT0103 aminotransferase, class III pyridoxal-phosphate dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.989
Swol_0683
KEGG: sat:SYN_02276 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
 
   
 0.668
ribBA
GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
     
 0.647
Swol_1222
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.643
Swol_0692
KEGG: mta:Moth_2198 putative transcriptional regulator, AsnC family.
     
 0.625
Swol_0693
Transcriptional regulator, AsnC family; KEGG: dsy:DSY2220 hypothetical protein.
     
 0.625
Swol_0691
KEGG: chy:CHY_1211 radical SAM domain protein.
  
  
 0.585
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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