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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0698Putative iron-sulfur-binding reductase; Oxidoreductase involved in syntrophic growth of S.wolfei with butyrate. Is presumed to link the electron flow from butyryl-CoA dehydrogenases to the membrane, in conjunction with the electron transfer flavoprotein EtfAB. May transfer electrons to the menaquinone pool of the membrane. (714 aa)    
Predicted Functional Partners:
etfB
Electron transfer flavoprotein, beta subunit; Part of an electron transfer flavoprotein involved in syntrophic growth of S.wolfei with butyrate. Probably receives electrons from butyryl-CoA dehydrogenases, and transfers them to the membrane-bound quinone oxidoreductase Swol_0698. Belongs to the ETF beta-subunit/FixA family.
 
  
 0.909
etfA
Electron transfer flavoprotein, alpha subunit; Part of an electron transfer flavoprotein involved in syntrophic growth of S.wolfei with butyrate. Probably receives electrons from butyryl-CoA dehydrogenases, and transfers them to the membrane-bound quinone oxidoreductase Swol_0698. Belongs to the ETF alpha-subunit/FixB family.
 
  
 0.884
Swol_2054
KEGG: cpe:CPE1014 probable flavoprotein.
  
  
 0.724
Swol_0395
Succinate dehydrogenase subunit C; KEGG: mta:Moth_0810 protein of unknown function DUF224, cysteine-rich region.
  
 
 0.721
Swol_1933
Conserved hypothetical protein; Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Catalyzes the oxidation of butanoyl-CoA to crotonyl-CoA. Probably passes the electrons released by this reaction on to electron-transfer flavoproteins (EtfAB) to finally generate hydrogen and/or formate.
  
  
 0.710
Swol_0800
KEGG: chy:CHY_0793 formate dehydrogenase-O, major subunit, selenocysteine-containing.
 
  
 0.695
Swol_0658
KEGG: tko:TK1612 glutamate synthase beta chain-related oxidoreductase, containing 2Fe-2S and 4Fe-4S clusters.
  
  
 0.664
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.620
Swol_0267
Electron transfer flavoprotein beta subunit-like protein; KEGG: sdy:SDY_0063 FixA.
 
  
 0.606
Swol_2122
KEGG: dsy:DSY4304 hypothetical protein.
 
  
 0.596
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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