Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swol_0806GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (734 aa)    
Predicted Functional Partners:
Swol_0090
KEGG: chy:CHY_0211 Ppx/GppA phosphatase.
 
 
 0.933
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.923
Swol_0082
KEGG: aae:aq_342 MazG protein.
  
 
 0.920
Swol_2273
KEGG: tte:TTE1850 oxygen-sensitive ribonucleoside-triphosphate reductase.
     
 0.906
Swol_0343
Transmembrane sensor domain-like protein; KEGG: sat:SYN_01481 adenylate cyclase.
     
 0.905
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.878
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
  
 
 
 0.877
rplI
LSU ribosomal protein L9P; Binds to the 23S rRNA.
  
 
   0.876
rpsL
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.875
dtd
D-Tyr-tRNAtyr deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
  
    0.874
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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