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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_0839KEGG: tte:TTE1450 predicted Rossmann-fold nucleotide-binding protein involved in DNA uptake. (362 aa)    
Predicted Functional Partners:
Swol_0188
KEGG: mta:Moth_0225 phosphoribosyltransferase.
 
 
 0.903
Swol_1595
KEGG: mta:Moth_0575 DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.881
Swol_1445
KEGG: mta:Moth_1022 Mg chelatase-related protein.
 
 0.860
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.838
Swol_0862
CheC, inhibitor of MCP methylation; KEGG: dsy:DSY2981 hypothetical protein.
  
    0.687
Swol_0538
Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A; KEGG: tte:TTE1266 leader peptidase (prepilin peptidase) / N-methyltransferase.
  
  
 0.680
Swol_1475
Endonuclease; KEGG: blo:BL0935 predicted endonuclease; Belongs to the UPF0102 family.
 
    0.669
trmFO
Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
       0.618
Swol_0531
KEGG: mta:Moth_1554 type II secretion system protein E.
  
  
 0.597
Swol_0702
KEGG: xac:XAC0531 hypothetical protein.
 
  
 0.596
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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