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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_1022KEGG: tte:TTE1568 thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (487 aa)    
Predicted Functional Partners:
Swol_0318
KEGG: mta:Moth_1277 small GTP-binding protein domain.
  
 0.970
Swol_1020
KEGG: tte:TTE1073 Biotin synthase and related enzymes.
 
  
 0.943
Swol_1023
Uncharacterized protein; Ortholog of Thermotoga maritima GenBank Accession Number AAD36341; KEGG: cac:CAC0487 uncharacterized protein, ortholog of Thermotoga maritima (4981823).
 
   
 0.891
thiC
Thiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.834
Swol_1017
KEGG: mta:Moth_1717 iron hydrogenase, small subunit.
 
   
 0.796
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.792
Swol_1021
Hypothetical protein.
       0.783
Swol_1925
KEGG: sat:SYN_01370 iron only hydrogenase large subunit.
 
   
 0.752
Swol_2436
KEGG: det:DET0147 [Fe] hydrogenase, large subunit HymC, putative.
 
   
 0.749
Swol_1793
KEGG: sat:SYN_02359 serine phosphatase RsbU, regulator of sigma subunit.
   
  
 0.672
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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