STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_1445KEGG: mta:Moth_1022 Mg chelatase-related protein. (511 aa)    
Predicted Functional Partners:
Swol_0839
KEGG: tte:TTE1450 predicted Rossmann-fold nucleotide-binding protein involved in DNA uptake.
 
 0.860
Swol_1475
Endonuclease; KEGG: blo:BL0935 predicted endonuclease; Belongs to the UPF0102 family.
 
  
 0.826
Swol_0188
KEGG: mta:Moth_0225 phosphoribosyltransferase.
 
  
 0.782
Swol_1595
KEGG: mta:Moth_0575 DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.604
Swol_1444
KEGG: mta:Moth_0580 hypothetical protein.
       0.508
Swol_0601
KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator.
  
  
 0.501
Swol_1442
Methionine synthase (B12-dependent); KEGG: pca:Pcar_2722 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation.
     
 0.427
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
     0.416
ruvC
Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
   
 0.407
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.402
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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