close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_1659SPFH domain, Band 7 family protein; KEGG: bxe:Bxe_C0544 hypothetical protein. (262 aa)    
Predicted Functional Partners:
ftsH
FtsH-2 peptidase. Metallo peptidase. MEROPS family M41; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
   
 0.848
Swol_1258
Vesicle-fusing ATPase; KEGG: tte:TTE0122 ATP-dependent Zn proteases; Belongs to the AAA ATPase family.
   
 0.847
Swol_1658
Hypothetical protein.
       0.783
Swol_1862
KEGG: mth:MTH693 hypothetical protein.
 
  
 0.649
Swol_0910
KEGG: chy:CHY_1148 peptidase, M16 family; Belongs to the peptidase M16 family.
  
 0.563
Swol_2049
KEGG: tte:TTE0400 uncharacterized membrane protein (homolog of Drosophila rhomboid).
   
 0.547
Swol_1101
KEGG: tte:TTE1778 uridine kinase.
  
  0.478
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.477
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
 
 0.450
Swol_1442
Methionine synthase (B12-dependent); KEGG: pca:Pcar_2722 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation.
   
 0.433
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.