STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_1710Hydrolase (metallo-beta-lactamase superfamily)-like protein; KEGG: mta:Moth_1254 beta-lactamase-like. (390 aa)    
Predicted Functional Partners:
Swol_1595
KEGG: mta:Moth_0575 DNA internalization-related competence protein ComEC/Rec2.
 
   
0.709
sigA
Sigma 38 (RpoS); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.681
Swol_1596
KEGG: mta:Moth_0570 competence protein ComEA helix-hairpin-helix region.
 
  
 0.661
Swol_1600
KEGG: det:DET1460 methylated-DNA--protein-cysteine methyltransferase.
  
  
 0.650
Swol_0538
Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A; KEGG: tte:TTE1266 leader peptidase (prepilin peptidase) / N-methyltransferase.
 
  
 0.592
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.585
Swol_0839
KEGG: tte:TTE1450 predicted Rossmann-fold nucleotide-binding protein involved in DNA uptake.
 
  
 0.583
Swol_1711
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.583
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.547
Swol_0533
KEGG: mta:Moth_1552 type II secretion system protein.
 
  
 0.542
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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