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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_1934acetyl-CoA acetyltransferase; Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Probably catalyzes the beta- keto thiolysis of acetoacetyl-CoA, leading to 2 acetyl-CoA molecules. (396 aa)    
Predicted Functional Partners:
Swol_1935
3-hydroxyacyl-CoA dehydrogenase; Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Probably catalyzes the oxidation of 3-hydroxybutyryl-CoA to acetoacetyl-CoA. Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 
 0.968
Swol_0767
Phosphotransacetylase; KEGG: ctc:CTC01239 phosphate acetyltransferase.
    
 0.948
Swol_0559
Biotin carboxylase / acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.927
Swol_0375
KEGG: dsy:DSY3883 hypothetical protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.924
Swol_2139
KEGG: mta:Moth_2251 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.924
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.924
Swol_1936
Short chain enoyl-CoA hydratase; Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Probably catalyzes the hydration of crotonyl-CoA to 3-hydroxybutyryl-CoA.
 
 0.923
Swol_2030
KEGG: cac:CAC2708 3-hydroxybutyryl-CoA dehydrogenase.
 
 0.923
Swol_0435
KEGG: chy:CHY_1603 3-hydroxybutyryl-CoA dehydrogenase.
 
 0.919
Swol_1048
KEGG: bcz:BCZK0420 formate C-acetyltransferase (formate acetyltransferase) (pyruvate formate-lyase).
     
 0.911
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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