Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swol_2019RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: sth:STH845 RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)    
Predicted Functional Partners:
Swol_2018
Putative transmembrane anti-sigma factor.
  
 
 0.891
rpoB
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.681
rpoC
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.678
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.667
Swol_2058
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: cac:CAC1509 specialized sigma subunit of RNA polymerase; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.634
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.619
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.577
Swol_1791
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: cac:CAC1509 specialized sigma subunit of RNA polymerase; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.571
Swol_0131
KEGG: mta:Moth_2363 putative transmembrane transcriptional regulator (anti-sigma factor).
  
 
 0.542
Swol_1213
Hypothetical protein.
  
 
 0.542
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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