STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_2052Conserved hypothetical protein; Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Catalyzes the oxidation of butanoyl-CoA to crotonyl-CoA. Probably passes the electrons released by this reaction on to electron-transfer flavoproteins (EtfAB) to finally generate hydrogen and/or formate. (610 aa)    
Predicted Functional Partners:
etfA
Electron transfer flavoprotein, alpha subunit; Part of an electron transfer flavoprotein involved in syntrophic growth of S.wolfei with butyrate. Probably receives electrons from butyryl-CoA dehydrogenases, and transfers them to the membrane-bound quinone oxidoreductase Swol_0698. Belongs to the ETF alpha-subunit/FixB family.
 
 
 0.799
Swol_0266
KEGG: dsy:DSY3797 hypothetical protein.
 
 
 0.774
etfB
Electron transfer flavoprotein, beta subunit; Part of an electron transfer flavoprotein involved in syntrophic growth of S.wolfei with butyrate. Probably receives electrons from butyryl-CoA dehydrogenases, and transfers them to the membrane-bound quinone oxidoreductase Swol_0698. Belongs to the ETF beta-subunit/FixA family.
 
 
 0.761
Swol_1484
Short chain enoyl-CoA hydratase; KEGG: cpe:CPE2301 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.749
Swol_1144
KEGG: pae:PA2893 acyl-CoA synthase.
 
 
 0.734
Swol_2121
KEGG: pai:PAE3587 electron transfer flavoprotein alpha subunit.
 
 
 0.732
Swol_2122
KEGG: dsy:DSY4304 hypothetical protein.
 
 
 0.731
Swol_0267
Electron transfer flavoprotein beta subunit-like protein; KEGG: sdy:SDY_0063 FixA.
 
 
 0.712
Swol_2133
KEGG: gme:Gmet_0107 hypothetical protein.
  
     0.705
Swol_2134
KEGG: gme:Gmet_0108 ATPase associated with various cellular activities, AAA_5.
  
     0.702
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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