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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_2181Peroxiredoxin-like protein; KEGG: gme:Gmet_2723 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. (81 aa)    
Predicted Functional Partners:
Swol_2182
KEGG: aae:aq_486 alkyl hydroperoxide reductase.
     0.985
Swol_2054
KEGG: cpe:CPE1014 probable flavoprotein.
  
  
 0.867
Swol_1300
KEGG: ctc:CTC02552 thioredoxin reductase.
  
 
 0.786
Swol_2471
KEGG: chy:CHY_0906 thioredoxin-disulfide reductase.
  
 
 0.786
Swol_0462
Thioredoxin; KEGG: sth:STH2404 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.671
Swol_0660
KEGG: tte:TTE1252 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
  
 0.550
Swol_1892
KEGG: sth:STH1882 Fur family transcriptional regulator; Belongs to the Fur family.
  
  
 0.550
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.541
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.538
Swol_0658
KEGG: tko:TK1612 glutamate synthase beta chain-related oxidoreductase, containing 2Fe-2S and 4Fe-4S clusters.
 
  
 0.490
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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