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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swol_2453Cardiolipin synthetase 2; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (485 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.540
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.519
Swol_1595
KEGG: mta:Moth_0575 DNA internalization-related competence protein ComEC/Rec2.
   
 
 0.518
Swol_1101
KEGG: tte:TTE1778 uridine kinase.
 
  
 0.499
Swol_1084
Non-ribosomal peptide synthetase modules and related proteins-like protein; KEGG: bld:BLi00402 lichenysin synthetase B; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.490
glyA
Ribose-5-phosphate isomerase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.488
Swol_2452
Carbonic anhydrase-like protein; KEGG: hma:rrnAC0751 carbonic anhydrase.
       0.478
Swol_0601
KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator.
   
 
 0.448
Swol_1945
KEGG: ctc:CTC02325 putative activator of (R) -2-hydroxyglutaryl-coA dehydratase.
 
    0.448
Swol_1345
KEGG: sth:STH1669 1-acyl-sn-glycerol-3-phosphate acyltransferase.
  
 
 0.444
Your Current Organism:
Syntrophomonas wolfei Goettingen
NCBI taxonomy Id: 335541
Other names: S. wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen, Syntrophomonas wolfei subsp. wolfei str. Goettingen G311, Syntrophomonas wolfei subsp. wolfei str. Gottingen, Syntrophomonas wolfei subsp. wolfei strain Goettingen
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