STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfum_0603Hypothetical protein. (247 aa)    
Predicted Functional Partners:
Sfum_0604
PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: dps:DP0805 similar to beta-phosphoglucomutase.
       0.700
Sfum_0090
KEGG: dvu:DVU3144 cytochrome c family protein.
    
   0.568
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
   0.568
Sfum_1987
PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: sma:SAV6451 subtilisin-like protease.
    
   0.499
Sfum_2279
PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: sth:STH718 bacillopeptidase-like protein.
    
   0.499
Sfum_2858
KEGG: tbd:Tbd_1693 hypothetical protein.
    
   0.499
Sfum_2919
Fervidolysin. Serine peptidase. MEROPS family S08A; PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; cellulosome anchoring protein, cohesin region; cell surface receptor IPT/TIG domain protein; KEGG: ava:Ava_0365 peptidase S8 and S53, subtilisin, kexin, sedolisin.
    
   0.499
Sfum_0605
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.442
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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