STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfum_1388PFAM: peptidase M48, Ste24p; KEGG: sat:SYN_03230 Zn-dependent protease with chaperone function. (435 aa)    
Predicted Functional Partners:
Sfum_1925
Hypothetical protein; KEGG: bld:BLi02343 YpbR.
     
 0.837
Sfum_1389
PFAM: protein of unknown function DUF554; KEGG: rxy:Rxyl_1278 protein of unknown function DUF554.
       0.773
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.514
Sfum_1387
Hypothetical protein; KEGG: mja:MJ0737 rubredoxin-like non-heme iron protein.
       0.458
Sfum_1461
KEGG: gsu:GSU1212 hypothetical protein.
    
   0.431
Sfum_2322
KEGG: gme:Gmet_1198 hypothetical protein.
    
   0.431
Sfum_0261
PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: noc:Noc_1382 heat shock protein DnaJ-like.
  
 
 0.413
Sfum_1483
PFAM: heat shock protein DnaJ domain protein; KEGG: mlo:mlr0945 probable heat shock protein.
  
 
 0.413
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.413
Sfum_2364
PFAM: heat shock protein DnaJ domain protein; KEGG: lpf:lpl2001 chaperone protein DnaJ (heat shock protein).
  
 
 0.413
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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