STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moaAGTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa)    
Predicted Functional Partners:
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
ribBA
GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.909
folE2
GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
  0.900
Sfum_1700
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.891
Sfum_0070
TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: sat:SYN_02931 hypothetical cytosolic protein.
 
  
 0.887
Sfum_3076
Molybdenum cofactor synthesis domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.880
Sfum_0615
Molybdenum cofactor synthesis domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.868
Sfum_0559
PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; KEGG: mxa:MXAN_3956 putative adenylate cyclase.
  
 0.836
Sfum_1184
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: ret:RHE_PE00177 probable adenylate cyclase protein.
  
 0.831
Sfum_0907
Putative PAS/PAC sensor protein; PFAM: GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ava:Ava_0091 adenylate/guanylate cyclase.
  
 
  0.821
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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