STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpxThiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (171 aa)    
Predicted Functional Partners:
Sfum_0536
Signal peptidase I. Serine peptidase. MEROPS family S26A; KEGG: sat:SYN_01527 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Belongs to the peptidase S26 family.
   
  
 0.854
Sfum_1767
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.824
Sfum_3417
Manganese and iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.824
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.607
Sfum_0478
TIGRFAM: cysteine synthases; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; cysteinyl-tRNA synthetase, class Ia; KEGG: sat:SYN_00075 cysteinyl-tRNA synthetase.
  
  
 0.580
Sfum_2341
PFAM: type IV pilus assembly PilZ.
       0.578
Sfum_1708
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: dde:Dde_2067 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.534
Sfum_4096
PFAM: Thioredoxin domain; KEGG: sat:SYN_02089 thioredoxin.
  
 
 0.534
Sfum_3874
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glutaredoxin; KEGG: dvu:DVU0283 AhpF family protein/thioredoxin reductase.
  
  
 0.520
Sfum_2681
TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: sth:STH1137 cysteine synthase.
   
  
 0.518
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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