STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfum_2443Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: det:DET1293 sensory box sensor histidine kinase. (578 aa)    
Predicted Functional Partners:
Sfum_2442
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: ade:Adeh_3729 two component, sigma54 specific, transcriptional regulator, fis family.
 
 
   0.894
Sfum_2303
PFAM: response regulator receiver; KEGG: tcx:Tcr_2179 response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase.
 
 
 0.805
Sfum_0735
KEGG: mbu:Mbur_0639 multisensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 
 0.791
Sfum_3517
PAS/PAC sensor signal transduction histidine kinase; KEGG: sat:SYN_01077 sensor proteinLuxQ; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.784
Sfum_0648
PFAM: response regulator receiver; KEGG: dvu:DVU3238 response regulator.
 
   0.781
Sfum_0633
PFAM: response regulator receiver; KEGG: dps:DP1491 similar to two-component system response regulator (Ntr family).
 
   0.780
Sfum_0632
PFAM: response regulator receiver; KEGG: dvu:DVU2963 response regulator.
 
   0.774
Sfum_0636
PFAM: response regulator receiver; KEGG: dvu:DVU3215 response regulator.
 
 
   0.771
Sfum_0620
PFAM: response regulator receiver; KEGG: dvu:DVU2394 sigma-54 dependent transcriptional regulator/response regulator.
 
   0.770
Sfum_0618
PFAM: response regulator receiver; KEGG: dvu:DVU3215 response regulator.
 
   0.766
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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