STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfum_2941Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: rpc:RPC_3945 transcriptional regulator, Crp/Fnr family. (235 aa)    
Predicted Functional Partners:
Sfum_1184
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: ret:RHE_PE00177 probable adenylate cyclase protein.
  
 0.894
Sfum_1320
Hypothetical protein; KEGG: jan:Jann_2863 endonuclease.
   
 0.772
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.756
aqpZ
MIP family channel proteins; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.751
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.739
Sfum_0559
PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; KEGG: mxa:MXAN_3956 putative adenylate cyclase.
  
 0.682
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.656
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.642
Sfum_1513
PFAM: cyclic nucleotide-binding; Rhodanese domain protein; KEGG: ttj:TTHA1437 transcription regulator, Crp family.
  
  
 0.620
Sfum_0558
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; KEGG: sat:SYN_01481 adenylate cyclase.
  
 0.616
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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