STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfum_2952PFAM: nickel-dependent hydrogenase, large subunit; KEGG: dde:Dde_2138 periplasmic (NiFe) hydrogenase, large subunit, isozyme 1; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (546 aa)    
Predicted Functional Partners:
Sfum_2953
KEGG: dde:Dde_2137 hydrogenase (NiFe) small subunit (HydA); TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein.
 
 
 0.999
Sfum_2951
TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52, hydrogen uptake protein; KEGG: dde:Dde_2139 hydrogenase expression/formation protein.
 
 
 0.961
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.951
Sfum_1050
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; methyl-viologen-reducing hydrogenase, delta subunit; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: afu:AF0662 heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta.
  
 
 0.938
Sfum_1286
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; methyl-viologen-reducing hydrogenase, delta subunit; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cte:CT0867 heterodisulfide reductase, subunit A/hydrogenase, delta subunit, putative.
  
 
 0.938
Sfum_0822
Formate dehydrogenase, beta subunit (F420); PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mmp:MMP1297 formate dehydrogenase beta subunit.
  
 
 0.929
Sfum_0390
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: dvu:DVU3033 iron-sulfur cluster-binding protein.
  
 
 0.900
Sfum_0013
PFAM: methyl-viologen-reducing hydrogenase, delta subunit; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: dps:DP3052 similar to iron-sulfur binding reductase.
  
 
 0.897
Sfum_1792
PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: dps:DP1012 similar to methyl viologen-reducing hydrogenase, gamma chain.
  
 
 0.872
Sfum_2222
PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: deh:cbdb_A596 hydrogenase, group 3, VhuG subunit.
  
 
 0.872
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.