STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfum_3520PFAM: Silent information regulator protein Sir2; KEGG: gme:Gmet_0397 silent information regulator protein Sir2. (280 aa)    
Predicted Functional Partners:
Sfum_3244
Glutamate dehydrogenase (NAD/NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: mbu:Mbur_1973 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.724
Sfum_3265
Glutamate dehydrogenase (NAD/NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: mbu:Mbur_1973 Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.724
Sfum_0569
KEGG: sat:SYN_01420 hypothetical cytosolic protein.
   
  
 0.637
Sfum_3306
KEGG: pca:Pcar_0825 nicotinamide mononucleotide adenylyltransferase.
   
  
 0.637
Sfum_1472
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.607
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.581
Sfum_0343
KEGG: mca:MCA1306 DnaK-related protein.
   
 0.581
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.581
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.560
Sfum_2077
PFAM: AMP-dependent synthetase and ligase; KEGG: afu:AF0976 acetyl-CoA synthetase (acs-5).
   
 0.560
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.