STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
prs-2Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)    
Predicted Functional Partners:
Sfum_0449
Transketolase domain protein; PFAM: Transketolase, central region; Transketolase domain protein; KEGG: bha:BH0777 acetoin dehydrogenase (TPP-dependent) beta chain.
  
 0.974
Sfum_2647
PFAM: Transketolase, central region; Transketolase domain protein; KEGG: nph:NP0558A 2-oxoacid dehydrogenase E1 component, beta subunit.
  
 0.974
Sfum_1302
PFAM: Transketolase domain protein; Transketolase, central region; KEGG: tma:TM1762 transketolase.
   
 
 0.950
rplY
LSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
  
 0.937
Sfum_0481
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sat:SYN_00938 phosphomannomutase.
  
 0.929
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.925
Sfum_0268
KEGG: bfs:BF1288 putative amidophosphoribosyltransferase precursor.
  
 0.925
Sfum_0227
PFAM: NUDIX hydrolase; KEGG: nma:NMA1263 ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.
  
 
 0.919
Sfum_0934
TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: gme:Gmet_2621 ribose/galactose isomerase.
    
 0.917
Sfum_1376
TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase; KEGG: aae:aq_1138 ribose 5-phosphate isomerase B.
    
 0.917
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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