STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfum_3737Putative two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: gsu:GSU0841 sigma-54 dependent DNA-binding response regulator. (469 aa)    
Predicted Functional Partners:
Sfum_2069
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.776
Sfum_1383
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: gme:Gmet_0428 NifH/FrxC:cobyrinic acid a,c-diamide synthase.
  
 
 0.628
Sfum_1502
Signal transduction histidine kinase, nitrogen specific, NtrB; KEGG: deh:cbdb_A1591 sensor histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.606
Sfum_0294
KEGG: ade:Adeh_2805 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.529
Sfum_1650
CheA signal transduction histidine kinases; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: dde:Dde_1577 CheA signal transduction histidine kinases.
  
 
 0.495
Sfum_3738
KEGG: mag:amb0553 response regulator; TIGRFAM: metal dependent phophohydrolase; PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; HDOD; SMART: metal-dependent phosphohydrolase, HD region.
  
 
 0.489
Sfum_0854
Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: dps:DP2891 similar to two-component system sensor histidine kinase (Ntr family).
 
 
 0.484
Sfum_1487
KEGG: pca:Pcar_1993 signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein.
 
 
 0.484
Sfum_2495
KEGG: hch:HCH_03588 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.484
Sfum_3740
PAS/PAC sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein.
  
 
 0.480
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.