STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sfum_4101KEGG: deh:cbdb_A478 hypothetical protein. (529 aa)    
Predicted Functional Partners:
Sfum_2728
PFAM: protein of unknown function DUF101; KEGG: gme:Gmet_1615 protein of unknown function DUF101.
   
    0.948
Sfum_0259
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
  
 0.793
phnX2
TIGRFAM: phosphonoacetaldehyde hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: btk:BT9727_1215 possible phosphonoacetaldehyde hydrolase; Belongs to the HAD-like hydrolase superfamily. PhnX family.
  
    0.725
phnX
Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.
  
    0.725
Sfum_3315
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: gme:Gmet_1348 HAD-superfamily hydrolase subfamily IA, variant 3.
  
    0.725
Sfum_1119
TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein; KEGG: sat:SYN_00872 calcium-transporting ATPase.
 
  
 0.720
Sfum_2388
PAS/PAC sensor signal transduction histidine kinase; KEGG: rme:Rmet_4714 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
  
 0.621
Sfum_3243
KEGG: rxy:Rxyl_0093 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
  
 0.621
Sfum_3668
PAS/PAC sensor signal transduction histidine kinase; KEGG: rme:Rmet_4714 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
  
 0.621
folE2
GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate.
       0.614
Your Current Organism:
Syntrophobacter fumaroxidans
NCBI taxonomy Id: 335543
Other names: S. fumaroxidans MPOB, Syntrophobacter fumaroxidans DSM 10017, Syntrophobacter fumaroxidans MPOB, Syntrophobacter fumaroxidans str. MPOB, Syntrophobacter fumaroxidans strain MPOB, Syntrophobacter sp. DSM 10017, syntrophic propionate-oxidizing bacterium DSM 10017
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