STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiGProbable 3-demethylubiquinone-9 3-O-methyltransferase RP622; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (240 aa)    
Predicted Functional Partners:
ubiH
Putative ubiquinone biosynthesis monooxgenase COQ6.
 
 
 0.970
coq7
Coq7 family protein; Belongs to the COQ7 family.
  
 0.952
rpiB
Ribose-5-phosphate isomerase.
      0.908
ubiA
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
 
 0.777
aarF
Ubiquinone biosynthesis protein; AarF.
  
 0.749
AAZ21937.1
Hypothetical protein; Similar to COG1058: Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA.
 
      0.723
prfA
Protein release factor Class I (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
    0.662
hemK
HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
   
 0.660
lysC
Aspartate kinase; Belongs to the aspartokinase family.
       0.605
gcpE
Peptidoglycan acetylation; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.605
Your Current Organism:
Pelagibacter ubique HTCC1062
NCBI taxonomy Id: 335992
Other names: C. Pelagibacter ubique HTCC1062, Candidatus Pelagibacter ubique HTCC1062, Candidatus Pelagibacter ubique str. HTCC1062, Candidatus Pelagibacter ubique strain HTCC1062
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.