node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRG76272.1 | guaA | ABB30_10000 | ABB30_14345 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.950 |
KRG76272.1 | upp | ABB30_10000 | ABB30_05325 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.949 |
KRG78276.1 | guaA | ABB30_04245 | ABB30_14345 | Cytosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.456 |
KRG78276.1 | upp | ABB30_04245 | ABB30_05325 | Cytosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.962 |
glyA | guaA | ABB30_10915 | ABB30_14345 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.734 |
glyA | upp | ABB30_10915 | ABB30_05325 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.914 |
guaA | KRG76272.1 | ABB30_14345 | ABB30_10000 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
guaA | KRG78276.1 | ABB30_14345 | ABB30_04245 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Cytosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.456 |
guaA | glyA | ABB30_14345 | ABB30_10915 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.734 |
guaA | pyrB | ABB30_14345 | ABB30_01900 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.650 |
guaA | pyrD | ABB30_14345 | ABB30_14325 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.868 |
guaA | pyrF | ABB30_14345 | ABB30_01425 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.548 |
guaA | pyrH | ABB30_14345 | ABB30_07735 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.827 |
guaA | rpsB | ABB30_14345 | ABB30_07750 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. | 0.733 |
guaA | surE | ABB30_14345 | ABB30_07110 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.975 |
guaA | upp | ABB30_14345 | ABB30_05325 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.961 |
pyrB | guaA | ABB30_01900 | ABB30_14345 | Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.650 |
pyrB | pyrD | ABB30_01900 | ABB30_14325 | Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.981 |
pyrB | pyrF | ABB30_01900 | ABB30_01425 | Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.973 |
pyrB | pyrH | ABB30_01900 | ABB30_07735 | Aspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.478 |