UREG_00946 protein (Uncinocarpus reesii) - STRING interaction network

Nodes:

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

UREG_00946

Uncharacterized protein. (308 aa)

Predicted Functional Partners:

UREG_02354

0.919

UREG_02525

0.678

UREG_03598

0.673

UREG_01144

0.640

UREG_05532

0.606

UREG_06309

0.603

UREG_05720

0.557

UREG_05671

0.548

UREG_02031

0.537

UREG_02258

0.505

Your Current Organism:

Uncinocarpus reesii

NCBI taxonomy Id: 336963
Other names: U. reesii 1704, Uncinocarpus reesii 1704

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
UREG_00946	UREG_01144	C4JFD2	C4JGF3	Uncharacterized protein.	Peptidylprolyl isomerase.	0.640
UREG_00946	UREG_02031	C4JFD2	C4JK74	Uncharacterized protein.	Protein phosphatase PP2A regulatory subunit A.	0.537
UREG_00946	UREG_02258	C4JFD2	C4JEU8	Uncharacterized protein.	Developmental regulator flbA.	0.505
UREG_00946	UREG_02354	C4JFD2	C4JFM0	Uncharacterized protein.	Peptidylprolyl isomerase.	0.919
UREG_00946	UREG_02525	C4JFD2	C4JGC7	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.678
UREG_00946	UREG_03598	C4JFD2	C4JL90	Uncharacterized protein.	Uncharacterized protein.	0.673
UREG_00946	UREG_05532	C4JFD2	C4JSU3	Uncharacterized protein.	Uncharacterized protein.	0.606
UREG_00946	UREG_05671	C4JFD2	C4JT82	Uncharacterized protein.	NADH-ubiquinone oxidoreductase 19.3 kDa subunit; Belongs to the complex I 20 kDa subunit family.	0.548
UREG_00946	UREG_05720	C4JFD2	C4JTD1	Uncharacterized protein.	MHYT domain-containing protein.	0.557
UREG_00946	UREG_06309	C4JFD2	C4JXD6	Uncharacterized protein.	Phosphatase tensin-type domain-containing protein.	0.603
UREG_01144	UREG_00946	C4JGF3	C4JFD2	Peptidylprolyl isomerase.	Uncharacterized protein.	0.640
UREG_02031	UREG_00946	C4JK74	C4JFD2	Protein phosphatase PP2A regulatory subunit A.	Uncharacterized protein.	0.537
UREG_02031	UREG_02525	C4JK74	C4JGC7	Protein phosphatase PP2A regulatory subunit A.	ANK_REP_REGION domain-containing protein.	0.643
UREG_02258	UREG_00946	C4JEU8	C4JFD2	Developmental regulator flbA.	Uncharacterized protein.	0.505
UREG_02258	UREG_02525	C4JEU8	C4JGC7	Developmental regulator flbA.	ANK_REP_REGION domain-containing protein.	0.933
UREG_02258	UREG_05532	C4JEU8	C4JSU3	Developmental regulator flbA.	Uncharacterized protein.	0.499
UREG_02354	UREG_00946	C4JFM0	C4JFD2	Peptidylprolyl isomerase.	Uncharacterized protein.	0.919
UREG_02525	UREG_00946	C4JGC7	C4JFD2	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.678
UREG_02525	UREG_02031	C4JGC7	C4JK74	ANK_REP_REGION domain-containing protein.	Protein phosphatase PP2A regulatory subunit A.	0.643
UREG_02525	UREG_02258	C4JGC7	C4JEU8	ANK_REP_REGION domain-containing protein.	Developmental regulator flbA.	0.933

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

15

average node degree:

2.73

avg. local clustering coefficient:

0.859

expected number of edges:

10

PPI enrichment p-value:

0.105

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032957

Inositol trisphosphate metabolic process

4 of 5

3.24

4.19

2.40e-08

GO:0070266

Necroptotic process

4 of 13

2.83

3.59

2.27e-07

GO:0006066

Alcohol metabolic process

5 of 291

1.58

1.61

0.00014

GO:0052746

Inositol phosphorylation

2 of 3

3.16

1.54

0.0017

GO:0032958

Inositol phosphate biosynthetic process

2 of 14

2.5

0.97

0.0167

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000825

Inositol tetrakisphosphate 6-kinase activity

4 of 4

3.34

4.61

4.39e-09

GO:0051766

Inositol trisphosphate kinase activity

4 of 9

2.99

4.26

1.49e-08

GO:0003993

Acid phosphatase activity

3 of 7

2.97

2.88

5.66e-06

GO:0102732

myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity

2 of 2

3.34

1.83

0.00051

GO:0052726

inositol-1,3,4-trisphosphate 5-kinase activity

2 of 2

3.34

1.83

0.00051

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:30075

Acid phosphatase activity, and Alkaline phosphatase activity

6 of 14

2.97

6.68

3.23e-13

CL:30076

Acid phosphatase activity, and Phosphodiesterase I activity

4 of 7

3.1

4.32

1.27e-08

CL:38050

Inositol trisphosphate kinase activity, and Inositol tetrakisphosphate phosphatase activity

4 of 17

2.71

3.62

1.72e-07

CL:38074

Inositol phosphorylation, and Inositol tetrakisphosphate 5-kinase activity

3 of 5

3.12

2.98

3.89e-06

CL:30089

Alkaline phosphatase activity, and Acid phosphatase activity

2 of 7

2.8

1.41

0.0028

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00730

Thiamine metabolism

4 of 21

2.62

3.84

5.24e-08

map00740

Riboflavin metabolism

3 of 19

2.54

2.8

5.30e-06

map00562

Inositol phosphate metabolism

5 of 169

1.81

2.66

5.39e-07

map04070

Phosphatidylinositol signaling system

4 of 181

1.68

1.89

4.16e-05

map01100

Metabolic pathways

11 of 3242

0.87

0.96

5.24e-08

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1483249

Inositol phosphate metabolism

5 of 70

2.19

3.28

1.94e-07

MAP-196819

Vitamin B1 (thiamin) metabolism

2 of 5

2.94

1.47

0.0022

MAP-1855191

Synthesis of IPs in the nucleus

2 of 7

2.8

1.41

0.0028

MAP-1855167

Synthesis of pyrophosphates in the cytosol

2 of 10

2.64

1.3

0.0042

MAP-196849

Metabolism of water-soluble vitamins and cofactors

3 of 192

1.53

0.79

0.0228

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00149

Calcineurin-like phosphoesterase

3 of 14

2.67

2.15

0.00011

PF05770

Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain

2 of 2

3.34

1.6

0.0013

PF03770

Inositol polyphosphate kinase

2 of 9

2.69

1.15

0.0081

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