STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105518912L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (348 aa)    
Predicted Functional Partners:
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
   
 
 0.885
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 0.844
GAPDH
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.747
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.725
FH
Fumarate hydratase.
  
 0.693
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.670
SLC30A9
Solute carrier family 30 member 9.
  
    0.632
CYB5R4
Cytochrome b5 reductase 4.
   
 
 0.619
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.616
GOT1
Aspartate aminotransferase.
   
 0.608
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.