STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB7Serpin family B member 7; Belongs to the serpin family. (380 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.620
ALB
Albumin.
   
 
 0.551
TG
Thyroglobulin.
    
 0.540
IL4
Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.
      
 0.506
CSF2
Colony stimulating factor 2.
      
 0.497
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
      
 0.493
IL5
Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.
      
 0.493
IL13
Interleukin 13.
   
  
 0.490
VTN
SMB domain-containing protein.
   
 0.443
MB
Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
   
  
 0.425
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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