| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADIPOQ | GHRL | ENSCANP00000026668 | ENSCANP00000011877 | Adiponectin, C1Q and collagen domain containing. | Ghrelin and obestatin prepropeptide. | 0.519 |
| ADIPOQ | LEP | ENSCANP00000026668 | ENSCANP00000001549 | Adiponectin, C1Q and collagen domain containing. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.876 |
| ADIPOQ | LEPR | ENSCANP00000026668 | ENSCANP00000010929 | Adiponectin, C1Q and collagen domain containing. | Leptin receptor. | 0.538 |
| CNTF | EGFR | ENSCANP00000026168 | ENSCANP00000018140 | Ciliary neurotrophic factor. | Receptor protein-tyrosine kinase. | 0.823 |
| CNTF | EPO | ENSCANP00000026168 | ENSCANP00000031781 | Ciliary neurotrophic factor. | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | 0.840 |
| CNTF | EPOR | ENSCANP00000026168 | ENSCANP00000039396 | Ciliary neurotrophic factor. | Erythropoietin receptor; Receptor for erythropoietin. | 0.821 |
| CNTF | LEP | ENSCANP00000026168 | ENSCANP00000001549 | Ciliary neurotrophic factor. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.866 |
| CNTF | LEPR | ENSCANP00000026168 | ENSCANP00000010929 | Ciliary neurotrophic factor. | Leptin receptor. | 0.858 |
| CNTF | LIFR | ENSCANP00000026168 | ENSCANP00000021517 | Ciliary neurotrophic factor. | LIF receptor subunit alpha. | 0.977 |
| CNTF | PRL | ENSCANP00000026168 | ENSCANP00000012347 | Ciliary neurotrophic factor. | Prolactin. | 0.823 |
| EGFR | CNTF | ENSCANP00000018140 | ENSCANP00000026168 | Receptor protein-tyrosine kinase. | Ciliary neurotrophic factor. | 0.823 |
| EGFR | EPO | ENSCANP00000018140 | ENSCANP00000031781 | Receptor protein-tyrosine kinase. | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | 0.835 |
| EGFR | LEP | ENSCANP00000018140 | ENSCANP00000001549 | Receptor protein-tyrosine kinase. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.903 |
| EGFR | PRL | ENSCANP00000018140 | ENSCANP00000012347 | Receptor protein-tyrosine kinase. | Prolactin. | 0.882 |
| EPO | CNTF | ENSCANP00000031781 | ENSCANP00000026168 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Ciliary neurotrophic factor. | 0.840 |
| EPO | EGFR | ENSCANP00000031781 | ENSCANP00000018140 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Receptor protein-tyrosine kinase. | 0.835 |
| EPO | EPOR | ENSCANP00000031781 | ENSCANP00000039396 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Erythropoietin receptor; Receptor for erythropoietin. | 0.976 |
| EPO | GHR | ENSCANP00000031781 | ENSCANP00000021128 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Growth hormone receptor. | 0.823 |
| EPO | LEP | ENSCANP00000031781 | ENSCANP00000001549 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.897 |
| EPO | LEPR | ENSCANP00000031781 | ENSCANP00000010929 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Leptin receptor. | 0.823 |